20 Best Enzyme Drain Cleaners [2024]

Are you looking for the best enzyme drain cleaners? Based on expert reviews, we ranked them. We've listed our top-ranked picks, including the top-selling enzyme drain cleaners.

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# Preview Product
1 Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat... Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper,...
2 Zep Drain Defense Enzymatic Drain Cleaner Powder 18 Ounces (Case of 2) ZDC16 - Safe for Pipes and... Zep Drain Defense Enzymatic Drain Cleaner Powder 18 Ounces (Case of 2) ZDC16 - Safe for Pipes and...
3 ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
4 Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner -... Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner...
5 Roebic K-97 Main Line Cleaner, Exclusive Biodegradable Bacteria Digests Paper, Fats, and Grease in... Roebic K-97 Main Line Cleaner, Exclusive Biodegradable Bacteria Digests Paper, Fats, and Grease...
6 Green Gobbler BIO-Flow Drain Strips - 24 Strips | Drain Cleaner & Deodorizer Green Gobbler BIO-Flow Drain Strips - 24 Strips | Drain Cleaner & Deodorizer
7 Biokleen Bac-Out Enzymatic Drain Cleaner - 32 Ounce (2 Pack) - Enzyme Prevents Clogs, Eco-Friendly,... Biokleen Bac-Out Enzymatic Drain Cleaner - 32 Ounce (2 Pack) - Enzyme Prevents Clogs,...
8 48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe... 48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe...
9 Bio-Clean Ultimate Drain Cleaning Kit Cleans Drains- Septic Tanks - Grease Traps All Natural and... Bio-Clean Ultimate Drain Cleaning Kit Cleans Drains- Septic Tanks - Grease Traps All Natural and...
10 Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner,... Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener,...
11 Earthworm Drain Cleaner - Drain Deodorizer - Natural and Family-Safe - 64 fl oz Earthworm Drain Cleaner - Drain Deodorizer - Natural and Family-Safe - 64 fl oz
12 Biokleen Bac-Out Drain Cleaner - 32 Ounce - Deodorizes, Prevents Clogs, Eco-Friendly, Non-Toxic,... Biokleen Bac-Out Drain Cleaner - 32 Ounce - Deodorizes, Prevents Clogs, Eco-Friendly, Non-Toxic,...
13 Instant Power Enzyme Drain Cleaner, Drainage Clog Remover, 1-Gallon Instant Power Enzyme Drain Cleaner, Drainage Clog Remover, 1-Gallon
14 Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally... Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
15 SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors... SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate...
16 Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain &... Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain...
17 Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution- Stop... Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution-...
18 Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally... Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
19 Green Gobbler Ultimate Main Drain Opener | Drain Cleaner | Sewer Cleaner + Hair Clog Remover | 4... Green Gobbler Ultimate Main Drain Opener | Drain Cleaner | Sewer Cleaner + Hair Clog Remover | 4...
20 Drain Sticks Drain Cleaner Sticks Drain Stix DrainStix Drain Cleaner and Deodorizer Sticks... Drain Sticks Drain Cleaner Sticks Drain Stix DrainStix Drain Cleaner and Deodorizer Sticks...
SaleBestseller No. 1
Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat...
  • RAPID DEGRADATION TECHNOLOGY. Green Gobbler Enzyme Drain Cleaner degrades fats, oils, greases, starches, proteins, cellulose, sludge, and other food...
  • REDUCE PUMP-OUT FREQUENCY. Enzyme Drain Cleaner reduces the frequency of costly septic tank pump outs when used regularly. Increases the efficacy of...
  • TARGETS FOG, EVEN AS pH DECREASES. Green Gobbler Enzyme Drain Cleaner aids in the biological breakdown of organic material inside of drains and tanks....
  • ULTRA-FAST ODOR ELIMINATION. Green Gobbler Enzyme Drain Cleaner eliminates odors associated with drain lines, lift stations, sewers, septic tanks,...
  • GUARANTEED, OR YOUR MONEY BACK. Green Gobbler’s conscious creations are safer, stronger, and more effective than caustic chemicals. 30-day money...
Bestseller No. 2
Zep Drain Defense Enzymatic Drain Cleaner Powder 18 Ounces (Case of 2) ZDC16 - Safe for Pipes and...
  • Helps prevent clogs in sinks, toilets and showers
  • ENZYME BASED FORMULA: Breaks down drain-clogging elements. Use monthly to prevent future clogs from happening
  • SAFE FOR: PVC and most other septic systems
  • Certified, biodegradable formula, breaks down into carbon dioxide, minerals and water
  • BREAKS DOWN: Into CO2, minerals and water
Bestseller No. 3
ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
  • Cuts through grease, protein & hair buildup
  • Made with enzyme power
  • Safer for people, pets & the planet
  • Non-corrosive, won’t damage pipes
  • Made in USA without dyes, parabens, phosphates or phthalates
Bestseller No. 4
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner -...
  • Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most...
  • Powerful Cleaning Performance - Our super strength proprietary formulation breaks up and digests complex organic proteins, pet stains, hair, grease,...
  • Multi-Purpose Enzyme Cleaner - The drain odor eliminator is a special blend of powerful bacterial enzymes, detergent and deodorant, that prevents...
  • Deodorizer & Odor Eliminator - The dog enzyme cleaner and pet odor eliminator for home is a highly concentrated bacterial digestant for grease,...
  • Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral,...
SaleBestseller No. 5
Roebic K-97 Main Line Cleaner, Exclusive Biodegradable Bacteria Digests Paper, Fats, and Grease in...
  • PREVENTS CLOGS AND BACKUPS: Roebic K-97 Main Line Cleaner naturally breaks down waste such as paper, sludge, fats & grease to quickly restore proper...
  • BIODEGRADABLE BACTERIA FORMULA: Main Line Cleaner contains millions of specialized biodegradable waste degrading bacteria to powerfully and...
  • SAFE FOR ALL PLUMBING: K-97 treatment is safe on all pipes for any household and the environment to help keep your lines free of backups
  • IDEAL FOR LOW FLOW TOILETS: K-97 is indispensable in resolving the problems of sludge buildup due to the inefficiencies of "low flow" toilets by...
  • EASY TO USE: Simply shake well, pour 8 ounces into toilet, and flush (repeat for 4 consecutive days); Repeat four times a year, or as needed
SaleBestseller No. 6
Green Gobbler BIO-Flow Drain Strips - 24 Strips | Drain Cleaner & Deodorizer
  • ULTRA CONCENTRATED strips for powerful cleaning and deodorizing of household drain lines. Smelly drain? Bio-Flow Drain Strips will eat away at organic...
  • ELIMINATES & DIGESTS grease, oil, fats, scum and food quickly for easy drain cleaning. The gunk that’s stuck inside of your drain won’t stand a...
  • UTILIZES POWERFUL YET SLOW DISSOLVING enzymes to take care of lodged organic materials. Food and grease will stick to your drain like Velcro. Pretty...
  • SAFE ON ALL PIPES and septic systems (including old pipes and PVC pipes)
  • PERFECT AS PART of a monthly drain cleaning routine. Traditional Use: Once a month, drop one Bio-Flow strip into the drain for cleaning and...
Bestseller No. 7
Biokleen Bac-Out Enzymatic Drain Cleaner - 32 Ounce (2 Pack) - Enzyme Prevents Clogs, Eco-Friendly,...
  • PREVENTS DRAIN CLOGS AND ELIMINATES ODORS: Bac-Out Drain Care prevents clogs, and eliminates tough odors. Its gel coating action thoroughly coats...
  • KEEPS PETS AND KIDS IN MIND: Bac-Out Drain Care leaves no harsh fumes or residue, just cleaner pipes and less odor.
  • BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky...
  • PLANT-BASED PRODUCT: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates,...
  • NEVER TESTED ON ANIMALS AND MADE IN THE USA: Biokleen products are never tested on animals, use biodegradable ingredients and are proudly manufactured...
SaleBestseller No. 8
48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe...
  • 【BRAND EFFECT BUT COST-EFFECTIVE】Exactly the same unclog effect as the brand as seen on TV but more cost-effective. Achieve a fresh smelling drain...
  • 【BIODEGRADABLE & NATURAL】Perfect for the kitchen sinks, vanity, bathtub, toilet, showers, etc.
  • 【ONE STICK PER MONTH IS OK】 Each drain pipes takes only one cleaner stick measures 6.3 inches strip of organic enzymes. Once been applied, these...
  • 【SAVE HUNDREDS OF DOLLARS】Drain cleaner sticks are surely help reduce plumbing costs in a simple, sanitary, yet effective way. Say goodbye to high...
  • 【RELIABLE AFTER SALE SERVICE】 If you don't have a positive experience for ANY reason, we will do WHATEVER it takes to make sure you are 100%...
Bestseller No. 9
Bio-Clean Ultimate Drain Cleaning Kit Cleans Drains- Septic Tanks - Grease Traps All Natural and...
  • 100% All Natural Bacteria Enzymes
  • All The Tools You Need In One Convenient Box
  • Guaranteed To Fix Slow Running Drains!
  • Environmentally friendly and safe
  • Free Shipping
SaleBestseller No. 10
Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner,...
  • PROFESSIONAL STRENGTH Grease Trap Cleaner and Commercial drain opener.
  • SAVE MONEY & REPAIRS with GET SERIOUS Grease trap Treatment.
  • COMMERCIAL DRAIN CLEANER for slow draining sinks and lines. Keeps Grease Traps & Drains Flowing
  • ENZYME DRAIN OPENER cleans the pipes before the grease trap, grease trap & pipes leaving the trap.
  • ELIMINATES OFFENSIVE ODORS Safe on Pipes & Plumbing.
SaleBestseller No. 11
Earthworm Drain Cleaner - Drain Deodorizer - Natural and Family-Safe - 64 fl oz
  • Great For All Slow Running Drains,Sinks,Garbage Disposals-Safe and Effective.
  • Liquid Drain Cleaner/Opener, No harsh chemical residues; safer for children and pets.
  • Citrus & sage fragrance, keeping your drains smelling fresh.
  • Removes build-up and helps stop clogs before they start.
  • Natural enzymes won't damage plumbing.
Bestseller No. 12
Biokleen Bac-Out Drain Cleaner - 32 Ounce - Deodorizes, Prevents Clogs, Eco-Friendly, Non-Toxic,...
  • PREVENTS DRAIN CLOGS AND ELIMINATES ODORS: Bac-Out Drain Care prevents clogs, and eliminates tough odors. Its gel coating action thoroughly coats...
  • KEEPS PETS AND KIDS IN MIND: Bac-Out Drain Care leaves no harsh fumes or residue, just cleaner pipes and less odor.
  • BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky...
  • PLANT-BASED PRODUCT: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates,...
  • NEVER TESTED ON ANIMALS AND MADE IN THE USA: Biokleen products are never tested on animals, use biodegradable ingredients and are proudly manufactured...
Bestseller No. 13
Instant Power Enzyme Drain Cleaner, Drainage Clog Remover, 1-Gallon
  • CLEANS AND DEODORIZES: Bad odors in your kitchens and restrooms could indicate that your drain system is clogged; Instant Power clogged drain cleaner...
  • EFFECTIVE CLOG REMOVER: Our clog remover uses enzymes to breakdown and rinse away grease, food particles, and other materials that get stuck in your...
  • REDUCES COST: Our drain clog remover reduces drain blockage emergencies that disrupt business operations and minimizes the need for frequent grease...
  • NO HARSH CHEMICALS: Instant Power Enzyme Drain Cleaner does not use harmful acids and caustic ingredients; It contains powerful enzymes that clear...
  • ECO-FRIENDLY: Our environmentally friendly formula will digest fats, oils, and greases along with other organic waste that accumulate in drains and...
Bestseller No. 14
Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
  • Does not contain harsh chemicals
  • Natural Enzymes won't damage plumbing
  • Removes build up and helps stop clogs before they start
  • Keeps drains and garbage disposals smelling clean and fresh
  • No Fragrance
Bestseller No. 15
SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors...
  • SMART CLEANING: Sani Sticks cleaner, deodorizer and clog preventer are a powerful, safe and efficient way to eliminate embarrassing, foul odors from...
  • SMART CLEANING: Sani Sticks cleaner, deodorizer and clog preventer are a powerful, safe and efficient way to eliminate embarrassing, foul odors from...
  • ONE STICK IS ALL IT TAKES: Made with powerful, natural enzymes, each Sani Stick slowly releases a super concentrated blend of powerful enzymes that...
  • INNOVATIVE DESIGN: Sani Sticks drain deodorizer and cleaners are thin, cylindrical and only 6.3 inches long making them ideal for homes and...
  • SAFE TO USE ANYWHERE: Because these odor eliminating drain sticks are non-toxic and use enzymes to clean, they are safe to use in all drains from the...
Bestseller No. 16
Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain &...
  • ENZYME ACTIVATED: Our enzymatic formula contains natural live cultures that seek & destroy organic waste as a food source. Releasing powerful enzymes...
  • THE SCIENCE: Enzymes work to break down complex waste particles into smaller pieces that can be more easily consumed. These smaller...
  • READY TO USE & NO RESIDUE: Commercial-grade, maximum strength formula provides fast-acting, sustained stain & odor elimination that’s RELIABLE &...
  • MULTI-SURFACE: Formulated for efficiency & versatility, Bastion’s Probiotic Stain & Odor Remover can be used on hard surfaces, floors, carpets,...
  • FAMILY SAFE & ENVIRONMENTALLY FRIENDLY: Bastion Probiotic Stain & Odor Remover contains neither bleach nor chlorine. This product is non-toxic and...
Bestseller No. 17
Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution- Stop...
  • GREAT VALUE: The Essential Values Enzyme Cleaner (Gallon/128 FL OZ) is NON-CORROSIVE, NON-FLAMMABLE, NON-ACID & the most Cost-Effective Cleaner on the...
  • EXTRA CONCENTRATED | PROFESSIONAL GRADE FORMULA: **DILUTION IS REQUIRED** JUST use a few ounces PER PROJECT! Fast Acting and Powerful at cleaning ANY...
  • ENVIRONMENTALLY FRIENDLY: Our Multipurpose formula is EXTRA CONCENTRATED | PET FRIENDLY | | NON-CORROSIVE that works Excellent for both Residential &...
  • ALL-IN-ONE UNIVERSAL CLEANER! No Job is TOO TOUGH for our Enzyme Cleaner! Deep clean Kitchen Sinks, Toilets & Urinals, Floor Drains, Garbage...
  • 60 DAY MONEY BACK GUARANTEES: We Believe in Our Customers & Stand by ALL Our Products, IF NOT – No Questions Asked. Proudly Made in USA and Tested,...
Bestseller No. 18
Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
  • Does not contain harsh chemicals
  • Natural Enzymes won't damage plumbing
  • Removes build-up & helps stop clogs before they start
  • Keeps drains & garbage disposals smelling clean and fresh!
  • Fragrance Free
Bestseller No. 19
Green Gobbler Ultimate Main Drain Opener | Drain Cleaner | Sewer Cleaner + Hair Clog Remover | 4...
  • Dissolves grease, hair, oils, soap scum and paper products easily.
  • Perfect to use on pipes, toilets, sinks, tubs and in other main drain lines.
  • Made of a non-corrosive formula that’s safe in septic systems.
  • Uses its high density to cling to pipes and liquify drain obstructions.
  • Non-corrosive, non-caustic and odorless formula.
SaleBestseller No. 20
Drain Sticks Drain Cleaner Sticks Drain Stix DrainStix Drain Cleaner and Deodorizer Sticks...
  • ❤2022 NEW UPGRADED POWERFUL ENZYME: 2021 new drain sticks slowly release powerful enzyme in the drain, to prevent future clogs and eliminat smelly...
  • ❤FLEXIBLE & MORE EFFECTIVE: The Upgraded drain stix is Flexible and Non-fragile, they won't be broken during transportation. So they can be long...
  • ❤SUITABLE FOR ALL DRAIN PIPES: The Drain Stix for clogs and odors can be used in both plastic and metal drain pipes, 100% safe for home kitchen,...
  • ❤SAFE, NON-TOXIC & CONENIENT TO USE - The drain stix is unstained and undyed, it is health product for household, no need to worry about they will...
  • ❤24x7 Hours Support: Our mission is to offer great and helpful products to customers, and we offer 24x7 hours support. If you have any issue about...

Having trouble finding a great enzyme drain cleaners?

This problem is well understood by us because we have gone through the entire enzyme drain cleaners research process ourselves, which is why we have put together a comprehensive list of the best enzyme drain cleanerss available in the market today.

After hours of searching and using all the models on the market, we have found the best enzyme drain cleaners for 2023. See our ranking below!

How Do You Buy The Best Enzyme Drain Cleaners?

Do you get stressed out thinking about shopping for a great enzyme drain cleaners? Do doubts keep creeping into your mind?

We understand, because we’ve already gone through the whole process of researching enzyme drain cleaners, which is why we have assembled a comprehensive list of the greatest enzyme drain cleaners available in the current market. We’ve also come up with a list of questions that you probably have yourself.

John Harvards has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for enzyme drain cleaners that you consider buying. Your questions might include the following:

  • Is it worth buying an enzyme drain cleaners?
  • What benefits are there with buying an enzyme drain cleaners?
  • What factors deserve consideration when shopping for an effective enzyme drain cleaners?
  • Why is it crucial to invest in any enzyme drain cleaners, much less the best one?
  • Which enzyme drain cleaners are good in the current market?
  • Where can you find information like this about enzyme drain cleaners?

We’re convinced that you likely have far more questions than just these regarding enzyme drain cleaners, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for enzyme drain cleaners, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible enzyme drain cleaners. Make sure that you are only using trustworthy and credible websites and sources.

John Harvards provides an enzyme drain cleaners buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information.

How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available enzyme drain cleaners currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of enzyme drain cleaners has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an enzyme drain cleaners?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your enzyme drain cleaners.
  5. Customer Ratings: Number ratings grade enzyme drain cleaners objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their enzyme drain cleaners.
  7. Product Quality: You don’t always get what you pay for with an enzyme drain cleaners, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an enzyme drain cleaners is should be an indication of how long it will work out for you.

John Harvards always remembers that maintaining enzyme drain cleaners information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding enzyme drain cleaners is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly!

FAQ:

Q: What are enzyme drain cleaners and why use them?

A: – Liquid drain cleaner – Citrus and sage fragrance – Safe for all plumbing materials

Q: What is a good enzyme based cleaner?

A: – SAFELY CLEAN ALL YOUR HARD-SURFACE FLOORS. … – REMOVE FILMY GRIME AND DIRT WITHOUT LEAVING BEHIND RESIDUE. … – KEEP YOUR FAMILY SAFE FROM HARMFUL CHEMICALS AND VAPORS. … – CLEAN MORE SURFACE AREA THAN SIMILAR NATURAL CLEANING PRODUCTS. … – COMPLETELY REMOVE ODORS WITHOUT ARTIFICIAL FRAGRANCES. …

Q: How to clean out a drain with enzymes?

A: Remove the stopper. Unscrew or pull out the stopper in your drain. … Insert the snake down the pipe. You can get a more heavy duty drain snake from a hardware store,or you can use a disposable snake that comes with … Rotate the snake until it grabs hold of the hair. … Slowly pull the drain snake out of the drain. …

Q: Does Green Gobbler really work?

A: Green Gobbler is the most effective household drain cleaner that you can buy. it is also safe for the environment and everything that it touches.it is completely biodegradable and washes away down your drain with the water. However, because it is so effective, you cannot use it on your garbage disposal, dishwasher, or shower drains.

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