20 Best Enzyme Cleaners [2024]

Are you looking for the best enzyme cleaners? Based on expert reviews, we ranked them. We've listed our top-ranked picks, including the top-selling enzyme cleaners.

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1 Zeiff Pro-Grade Multi-Purpose Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For... Zeiff Pro-Grade Multi-Purpose Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For...
2 Angry Orange Odor Eliminator & Pet Stain Remover - Carpet Cleaner for Pets, Citrus Scented Dog Urine... Angry Orange Odor Eliminator & Pet Stain Remover - Carpet Cleaner for Pets, Citrus Scented Dog...
3 Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain &... Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain...
4 Simple Green Bio Dog Active Stain & Odor Remover - Enzyme Cleaner & Stain Remover for Carpet, Rugs &... Simple Green Bio Dog Active Stain & Odor Remover - Enzyme Cleaner & Stain Remover for Carpet, Rugs...
5 Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution- Stop... Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution-...
6 BUBBAS Super Strength Enzyme Cleaner - Pet Odor Eliminator - Carpet Stain Remover - Remove Dog & Cat... BUBBAS Super Strength Enzyme Cleaner - Pet Odor Eliminator - Carpet Stain Remover - Remove Dog &...
7 Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit (32 oz... Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit (32 oz...
8 Nanoskin Enzyme Bio-Enzymatic Cleaner/Odor Eliminator [NA-EZM128], 1 Gallons Nanoskin Enzyme Bio-Enzymatic Cleaner/Odor Eliminator [NA-EZM128], 1 Gallons
9 Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat... Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper,...
10 Kleen-Free Naturally Preformed Enzyme Cleaner (Original, 1-Gallon Concentrate) Kleen-Free Naturally Preformed Enzyme Cleaner (Original, 1-Gallon Concentrate)
11 BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover |... BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover |...
12 Naturally It's Clean Multi-Surface Cleaner Spray - Enzymes Clean Stains from Bathroom, Kitchen,... Naturally It's Clean Multi-Surface Cleaner Spray - Enzymes Clean Stains from Bathroom, Kitchen,...
13 Kleen Free Naturally Original Concentrate 32 fl oz Enzyme Cleaner, Enzyme Solution and Multi-Purpose... Kleen Free Naturally Original Concentrate 32 fl oz Enzyme Cleaner, Enzyme Solution and...
14 Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally... Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
15 Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit, Enzymatic Solution... Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit, Enzymatic Solution...
16 Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner,... Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener,...
17 ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
18 Stardrops - The Pink Stuff - The Miracle All Purpose Cleaning Paste Stardrops - The Pink Stuff - The Miracle All Purpose Cleaning Paste
19 Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home... Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for...
20 Biokleen Bac-Out Stain Remover for Clothes & Carpet - 128 Ounce - Enzyme, Destroys Stains & Odors... Biokleen Bac-Out Stain Remover for Clothes & Carpet - 128 Ounce - Enzyme, Destroys Stains & Odors...
SaleBestseller No. 1
Zeiff Pro-Grade Multi-Purpose Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For...
  • Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most...
  • Powerful Cleaning Performance - Our proprietary formulation breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily...
  • Multi-Purpose Enzyme Cleaner - The special blend of bacterial enzymes, detergent and deodorant, prevents clogging in drains, grease traps, septic...
  • Deodorizer & Odor Eliminator - Highly concentrated bacterial digestant for grease, stains, oils, & organic waste. Effectively eliminates foul odors...
  • Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral,...
SaleBestseller No. 2
Angry Orange Odor Eliminator & Pet Stain Remover - Carpet Cleaner for Pets, Citrus Scented Dog Urine...
  • DUAL ACTION - Our stain remover and pet odor eliminator for home will help you enjoy having your furry friends around without the messes! Our...
  • DESTROY STAINS AND SMELLS - This extremely effective dog urine odor eliminator spray doesn't just mask foul odors and stains, it destroys them upon...
  • MULTI-SURFACE USE - A versatile odor eliminator and carpet stain remover that can clean it all! This multi-surface enzyme cleaner for dog urine works...
  • CITRUS SCENT - Made from citrus enzymes and other natural ingredients, this pet stain and odor remover leaves a fruity fragrance behind with every...
  • CUSTOMER SATISFACTION - Add this enzymatic cleaner to the top of your list of pet supplies for dogs and puppies. If you have any questions or concerns...
Bestseller No. 3
Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain &...
  • ENZYME ACTIVATED: Our enzymatic formula contains natural live cultures that seek & destroy organic waste as a food source. Releasing powerful enzymes...
  • THE SCIENCE: Enzymes work to break down complex waste particles into smaller pieces that can be more easily consumed. These smaller...
  • READY TO USE & NO RESIDUE: Commercial-grade, maximum strength formula provides fast-acting, sustained stain & odor elimination that’s RELIABLE &...
  • MULTI-SURFACE: Formulated for efficiency & versatility, Bastion’s Probiotic Stain & Odor Remover can be used on hard surfaces, floors, carpets,...
  • FAMILY SAFE & ENVIRONMENTALLY FRIENDLY: Bastion Probiotic Stain & Odor Remover contains neither bleach nor chlorine. This product is non-toxic and...
Bestseller No. 4
Simple Green Bio Dog Active Stain & Odor Remover - Enzyme Cleaner & Stain Remover for Carpet, Rugs &...
  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
  • Use on porous surfaces such as carpet, rugs, pet bedding, fabric, upholstery, clothing, curtains, Auto upholstery, crates, tile, finished wood,...
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Safe for use around pets
  • Eliminates new, old and set-in stains
Bestseller No. 5
Enzyme Cleaner (1 Gallon / 128 Fl OZ), Drain Cleaner, Made in USA – Multi-Purpose Solution- Stop...
  • GREAT VALUE: The Essential Values Enzyme Cleaner (Gallon/128 FL OZ) is NON-CORROSIVE, NON-FLAMMABLE, NON-ACID & the most Cost-Effective Cleaner on the...
  • EXTRA CONCENTRATED | PROFESSIONAL GRADE FORMULA: **DILUTION IS REQUIRED** JUST use a few ounces PER PROJECT! Fast Acting and Powerful at cleaning ANY...
  • ENVIRONMENTALLY FRIENDLY: Our Multipurpose formula is EXTRA CONCENTRATED | PET FRIENDLY | | NON-CORROSIVE that works Excellent for both Residential &...
  • ALL-IN-ONE UNIVERSAL CLEANER! No Job is TOO TOUGH for our Enzyme Cleaner! Deep clean Kitchen Sinks, Toilets & Urinals, Floor Drains, Garbage...
  • 60 DAY MONEY BACK GUARANTEES: We Believe in Our Customers & Stand by ALL Our Products, IF NOT – No Questions Asked. Proudly Made in USA and Tested,...
Bestseller No. 6
BUBBAS Super Strength Enzyme Cleaner - Pet Odor Eliminator - Carpet Stain Remover - Remove Dog & Cat...
  • ELIMINATES THE STUFF OF STAINS AND STINKS: The bio-enzymatic spray activates on contact with ammonia crystals and organic matter and doesnt stop...
  • GIVE IT PERMISSION TO GO ANYWHERE IN YOUR HOUSE: You can trust it on carpets, floors, furniture, clothing, litter boxes, kennels, carrier, anywhere...
  • WELL-BEHAVED AROUND PETS AND KIDS: With no chlorine, no chemical propellants, and nothing that stains or fades colors, its your houses best friend....
  • 100% SATISFACTION GUARANTEED: If your worst stains and odors arent gone, neither is your money. Well give you a full refund, no questions asked.
Bestseller No. 7
Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit (32 oz...
  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
  • Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates,...
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Safe for use around pets
  • Eliminates new, old and set-in stains
Bestseller No. 8
Nanoskin Enzyme Bio-Enzymatic Cleaner/Odor Eliminator [NA-EZM128], 1 Gallons
  • Package Dimensions: 14 L x 9 H x 13 W (inches)
  • Package Weight : 36 pounds
  • Country of Origin : United States
  • Part number: NA-EZM128
SaleBestseller No. 9
Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat...
  • RAPID DEGRADATION TECHNOLOGY. Green Gobbler Enzyme Drain Cleaner degrades fats, oils, greases, starches, proteins, cellulose, sludge, and other food...
  • REDUCE PUMP-OUT FREQUENCY. Enzyme Drain Cleaner reduces the frequency of costly septic tank pump outs when used regularly. Increases the efficacy of...
  • TARGETS FOG, EVEN AS pH DECREASES. Green Gobbler Enzyme Drain Cleaner aids in the biological breakdown of organic material inside of drains and tanks....
  • ULTRA-FAST ODOR ELIMINATION. Green Gobbler Enzyme Drain Cleaner eliminates odors associated with drain lines, lift stations, sewers, septic tanks,...
  • GUARANTEED, OR YOUR MONEY BACK. Green Gobbler’s conscious creations are safer, stronger, and more effective than caustic chemicals. 30-day money...
Bestseller No. 10
Kleen-Free Naturally Preformed Enzyme Cleaner (Original, 1-Gallon Concentrate)
  • Effective on hard-to-reach surfaces like corners, cracks, tile grouting, and other crevices, this hypoallergenic and non-toxic cleaner is a safe and...
  • Kleen-Free Naturally's fast-acting, safe, and unique enzyme formula attacks, penetrates, and emulsifies the organic matter that holds dirt together,...
  • Power through stubborn organic stains by adding 1-2 ounces of this concentrate to laundry, and 1 ounce to 20 ounces of water for general cleaning
  • This pack includes one bottle containing 128 ounces of concentrated enzyme cleaner
Bestseller No. 11
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover |...
  • BEST PROFESSIONAL GRADE CLEANING SOLUTION: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring,...
  • PET STAIN AND ODOR MIRACLE: Bubba's uses natural dormant enzymes that become active upon hitting that strong smelling cat pee, billions of enzymes...
  • SATISFACTION GUARANTEED: Other pet odor enzyme sprays use active enzymes that are ineffective soon after you buy them. Bubba's dormant enzymes formula...
  • CARPET & RUG INSTITUTE CERTIFIED: Our Pet Pee Cleaner and Enzymatic Odor Remover is a Top Rated pet stain & odor miracle. Don't be disappointed by...
  • MANY USES: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and...
Bestseller No. 12
Naturally It's Clean Multi-Surface Cleaner Spray - Enzymes Clean Stains from Bathroom, Kitchen,...
  • EFFECTIVE CLEANING: Safely cleans any hard surface. Multi-Surface is great for walls, floors, granite, cabinets, drawers, countertops, furniture, and...
  • HOW IT WORKS: The Pure & Fresh Enzymes break down scum and grime into their basic elements. Multi-Surface provides the longest-lasting results and is...
  • ECO-FRIENDLY: Naturally It’s Clean products are safer than harsh chemicals for your home, your pets, and the environment. No harsh fumes, vapors,...
  • EASY TO USE: Naturally It’s Clean Multi-Surface Cleaner, in two (2) 24oz Ready-To-Use Spray Bottles (total 48oz), is easy to use. Just shake and...
  • MADE IN USA: Our products are produced in our facility in the USA. We are committed to offering the most effective and safest cleaning products for...
Bestseller No. 13
Kleen Free Naturally Original Concentrate 32 fl oz Enzyme Cleaner, Enzyme Solution and Multi-Purpose...
  • Effective on hard-to-reach surfaces like corners, cracks, tile grouting, and other crevices, cleaner is a safe and environmentally-friendly...
  • Kleen-Free Naturally's fast-acting, safe, and unique enzyme formula attacks, penetrates, and emulsifies the organic matter that holds dirt together,...
  • Power through stubborn organic stains by adding 1-2 ounces of this concentrate to laundry, and 1 ounce to 20 ounces of water for general cleaning.
  • This pack includes one bottle containing 32 ounces of concentrated enzyme cleaner.
Bestseller No. 14
Earthworm Fragrance Free Drain Cleaner - Drain Opener - Natural Enzymes, Environmentally...
  • Does not contain harsh chemicals
  • Natural Enzymes won't damage plumbing
  • Removes build up and helps stop clogs before they start
  • Keeps drains and garbage disposals smelling clean and fresh
  • No Fragrance
SaleBestseller No. 15
Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit, Enzymatic Solution...
  • ❤️ EASY CLEANUP - Pet Stain & Odor Miracle makes clean up fast and easy, so you can quickly return to having fun with your fur-baby. Only an...
  • 😊 INCREDIBLE VALUE - Pet Stain & Odor Miracle makes it very easy for you to clean every surface in your home - carpet, rug, hardwood, laminate,...
  • ⭐ HIGHEST QUALITY - All of Sunny & Honey’s products are made with the highest quality ingredients available, right here - in the beautiful USA. As...
  • 🌱 NATURAL CLEANING POWER - Pet Stain & Odor Miracle was created with your furry kids in mind! This bio-enzymatic formula is biodegradable,...
  • ✔ OUR PROMISE - If you are not 100% in LOVE with Pet Stain & Odor Miracle, send it back for a full refund. You have absolutely nothing to lose...
SaleBestseller No. 16
Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner,...
  • PROFESSIONAL STRENGTH Grease Trap Cleaner and Commercial drain opener.
  • SAVE MONEY & REPAIRS with GET SERIOUS Grease trap Treatment.
  • COMMERCIAL DRAIN CLEANER for slow draining sinks and lines. Keeps Grease Traps & Drains Flowing
  • ENZYME DRAIN OPENER cleans the pipes before the grease trap, grease trap & pipes leaving the trap.
  • ELIMINATES OFFENSIVE ODORS Safe on Pipes & Plumbing.
Bestseller No. 17
ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
  • Cuts through grease, protein & hair buildup
  • Made with enzyme power
  • Safer for people, pets & the planet
  • Non-corrosive, won’t damage pipes
  • Made in USA without dyes, parabens, phosphates or phthalates
Bestseller No. 18
Stardrops - The Pink Stuff - The Miracle All Purpose Cleaning Paste
  • WORKS LIKE A MIRACLE ! -The Pink Stuff paste made cleaning easier like never before, While saving you time, space & money Lasts way longer than any...
  • GREAT FOR ALL SURFACES -Remove stains,Grease or grime from just about anything, Stoves, Kitchen Floors,metal, ceramics, porcelain, marble, wood,...
  • NO SCRATCHES -Stardrops Paste wont leave any scratches or any streak. Works Instantly -removes stains from Rust, Pen, Marker, Crayons, Paint,...
  • Sparkling streak free shine
Bestseller No. 19
Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home...
  • CERTIFIED GENTLE AND SAFE Chlorine free and color safe. Safe to use around pets and children. No hazardous propellants, no residue left behind. So...
  • ELIMINATES STAINS, ODORS AND RESIDUE If it’s gross, it’s gone. Not just the stain, but the stink. From stinky yellow pet urine and feces to vomit...
  • EVERY SURFACE, EVERY TIME For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping...
  • ENZYME ACTIVATED The key is getting to the problem deep-down. This spray contains natural enzymes that are activated on contact with odors and stains,...
  • 100% SATISFACTION GUARANTEED An Amazon best seller—for a reason. If your stains and odors aren’t gone, neither is your money. We’ll refund it in...
Bestseller No. 20
Biokleen Bac-Out Stain Remover for Clothes & Carpet - 128 Ounce - Enzyme, Destroys Stains & Odors...
  • STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry,...
  • PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
  • BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky...
  • PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates,...
  • NEVER TESTED ON ANIMALS AND MADE IN THE USA: Biokleen products are never tested on animals, use biodegradable ingredients and are proudly manufactured...

Having trouble finding a great enzyme cleaners?

This problem is well understood by us because we have gone through the entire enzyme cleaners research process ourselves, which is why we have put together a comprehensive list of the best enzyme cleanerss available in the market today.

After hours of searching and using all the models on the market, we have found the best enzyme cleaners for 2023. See our ranking below!

How Do You Buy The Best Enzyme Cleaners?

Do you get stressed out thinking about shopping for a great enzyme cleaners? Do doubts keep creeping into your mind?

We understand, because we’ve already gone through the whole process of researching enzyme cleaners, which is why we have assembled a comprehensive list of the greatest enzyme cleaners available in the current market. We’ve also come up with a list of questions that you probably have yourself.

John Harvards has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for enzyme cleaners that you consider buying. Your questions might include the following:

  • Is it worth buying an enzyme cleaners?
  • What benefits are there with buying an enzyme cleaners?
  • What factors deserve consideration when shopping for an effective enzyme cleaners?
  • Why is it crucial to invest in any enzyme cleaners, much less the best one?
  • Which enzyme cleaners are good in the current market?
  • Where can you find information like this about enzyme cleaners?

We’re convinced that you likely have far more questions than just these regarding enzyme cleaners, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for enzyme cleaners, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible enzyme cleaners. Make sure that you are only using trustworthy and credible websites and sources.

John Harvards provides an enzyme cleaners buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information.

How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available enzyme cleaners currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of enzyme cleaners has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an enzyme cleaners?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your enzyme cleaners.
  5. Customer Ratings: Number ratings grade enzyme cleaners objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their enzyme cleaners.
  7. Product Quality: You don’t always get what you pay for with an enzyme cleaners, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an enzyme cleaners is should be an indication of how long it will work out for you.

John Harvards always remembers that maintaining enzyme cleaners information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding enzyme cleaners is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly!

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