20 Best Methyfolate [2024]

Are you looking for the best methyfolate? Based on expert reviews, we ranked them. We've listed our top-ranked picks, including the top-selling methyfolate.

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1 Empirical Labs, Liposomal B12/Methyfolate 2 fl oz Empirical Labs, Liposomal B12/Methyfolate 2 fl oz
2 L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,... L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated |...
3 NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90... NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90...
4 Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO,... Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO,...
5 Nutricost Methyl Folate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO Nutricost Methyl Folate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO
6 L Methyl Folate 15mg Plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports... L Methyl Folate 15mg Plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form -...
7 Methyl Folate 1000 mcg | 200 Capsules | 5-MTHF | Folic Acid Supplement | Non-GMO, Gluten Free... Methyl Folate 1000 mcg | 200 Capsules | 5-MTHF | Folic Acid Supplement | Non-GMO, Gluten Free...
8 Jarrow Formulas Methyl Folate 400 mcg - 60 Veggie Caps, Pack of 2 - Highly Biologically Active Form... Jarrow Formulas Methyl Folate 400 mcg - 60 Veggie Caps, Pack of 2 - Highly Biologically Active...
9 Healthy Origins Methyl Folate (Quatrefolic) 800 mcg, 120 Veggie Caps Healthy Origins Methyl Folate (Quatrefolic) 800 mcg, 120 Veggie Caps
10 NOW Supplements, Methyl Folate 5000 mcg, Superior Bioavailability, 50 Veg Capsules NOW Supplements, Methyl Folate 5000 mcg, Superior Bioavailability, 50 Veg Capsules
11 Doctor's Best Fully Active Folate with Quatrefolic NonGMO Vegan Gluten Free 400 mcg Veggie Caps, 90... Doctor's Best Fully Active Folate with Quatrefolic NonGMO Vegan Gluten Free 400 mcg Veggie Caps,...
12 Neurobiologix Methylation Complete™ 120 Sublingual Tablets with Bioactive B12, Methyl Folate with... Neurobiologix Methylation Complete™ 120 Sublingual Tablets with Bioactive B12, Methyl Folate...
13 Douglas Laboratories Methyl Folate L-5-MTHF | 1,000 mcg Metafolin Identical to The Naturally... Douglas Laboratories Methyl Folate L-5-MTHF | 1,000 mcg Metafolin Identical to The Naturally...
14 L-Methylfolate 15mg - 90 Capsules - Professional Strength Active Methyl Folate - 5-MTHF Supplement... L-Methylfolate 15mg - 90 Capsules - Professional Strength Active Methyl Folate - 5-MTHF...
15 Our Daily Vites L-Methylfolate 15 mg / 15000 mcg Maximum Strength Active Folate, 5-MTHF, Non-GMO,... Our Daily Vites L-Methylfolate 15 mg / 15000 mcg Maximum Strength Active Folate, 5-MTHF, Non-GMO,...
16 L Methylfolate 15mg – DNA Verified for Maximum Potency – Superior Bioavailability – 5-MTHF... L Methylfolate 15mg – DNA Verified for Maximum Potency – Superior Bioavailability – 5-MTHF...
17 Methyl-Life Purest L-Methylfolate 10 mg Pharmaceutical Grade Professional Strength Active Folate - 3... Methyl-Life Purest L-Methylfolate 10 mg Pharmaceutical Grade Professional Strength Active Folate -...
18 DSO L-Methylfolate(5-MTHF) 10mg 90 Capsules Active Folate Homocysteine Control Anxiety Relief Folic... DSO L-Methylfolate(5-MTHF) 10mg 90 Capsules Active Folate Homocysteine Control Anxiety Relief...
19 Methyl Folate 15mg (120 Capsules) | Non-GMO, Gluten-Free with Professional Strength Vegan... Methyl Folate 15mg (120 Capsules) | Non-GMO, Gluten-Free with Professional Strength Vegan...
20 L Methyl Folate 15mg Plus Glycine - 90 Capsules - Active L Methylfolate 5-MTHF Supplement Pills -... L Methyl Folate 15mg Plus Glycine - 90 Capsules - Active L Methylfolate 5-MTHF Supplement Pills -...
Bestseller No. 2
L Methylfolate 15mg | 120 Capsules | Value Size | Max Potency | Optimized and Activated | Non-GMO,...
  • Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
  • Each L-Methylfolate (5-MTHF) capsule provides you with 15 mg of this bioavailable form of folic acid
  • Folate, also referred to as Folic Acid, is a fully active B complex vitamin
  • Our professional formula is backed by our commitment to purity and potency
  • Manufactured in a facility that is GMP certified
SaleBestseller No. 3
NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90...
  • CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body...
  • METABOLICALLY ACTIVE FOLATE*/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to...
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our...
  • Packaged in the USA by a family owned and operated company since 1968
SaleBestseller No. 4
Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO,...
  • BIOLOGICALLY ACTIVE FOLIC ACID — Our Optimized Folate formula promotes both cardiovascular and cognitive health with 1700 mcg of folate in the form...
  • WHY FOLATE? – Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with heart and brain health. Folate, a B vitamin,...
  • HEART & BRAIN-FRIENDLY NUTRIENT – Because folate helps inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular...
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are...
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the...
Bestseller No. 5
Nutricost Methyl Folate 1000mcg, 120 Vegetarian Capsules - Gluten Free, Non-GMO
  • 120 Capsules Methyl Folate (120 Servings)
  • 1,000mcg Methyl Folate Per Serving
  • Vegetarian Capsules
  • Non-GMO & Gluten Free & 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
Bestseller No. 6
L Methyl Folate 15mg Plus Methyl B12 Cofactor - Professional Strength, Active 5-MTHF Form - Supports...
  • PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of...
  • ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body's methylation...
  • ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is...
  • BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
  • CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide...
SaleBestseller No. 7
Methyl Folate 1000 mcg | 200 Capsules | 5-MTHF | Folic Acid Supplement | Non-GMO, Gluten Free...
  • ESSENTIAL NUTRIENT: Methyl Folate is the active, more bioavailable form of the B-Vitamin Folic Acid
  • CONVENIENT FORM: Delivers 1000 mcg of this important nutrient in Quick-Release capsules
  • EXPERTLY CRAFTED: Specially formulated supplement derived from high-quality sourcing standards
  • HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Artificial Color & Flavoring & NON-GMO
Bestseller No. 8
Jarrow Formulas Methyl Folate 400 mcg - 60 Veggie Caps, Pack of 2 - Highly Biologically Active Form...
  • Methyl Folate - Jarrow Formulas Methyl Folate is a highly biologically active form of folate. Due to the body’s limited ability to transform...
  • Quatrefolic - Featuring 4th generation development in folate delivery, our patent-pending technology formula features increased stability and...
  • Benefits - Healthful diets with adequate folate may reduce the risk of having a child with a brain or spinal cord birth defect.*
  • Convenient Veggie Capsules - Each veggie capsule delivers 400 micrograms (mcg) of methyl folate. Take 1 capsule per day, with or without a meal, or as...
  • Superior Nutrition & Formulation - The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior...
Bestseller No. 9
Healthy Origins Methyl Folate (Quatrefolic) 800 mcg, 120 Veggie Caps
  • THE REVOLUTIONARY FOLATE: Healthy Origins Quatrefolic Methyl Folate is the glucosamine salt of (6S)-5-methyltetrahydrofolate and is structurally...
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product...
  • QUATREFOLIC VS FOLIC ACID: Traditional folic acid supplements are not biologically active and need to be converted to the metabolically active...
  • QUATREFOLIC TO THE RESCUE: Individuals suffering from inadequate or ineffective MTHFR enzyme production can rest easy knowing that they are taking a...
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when...
Bestseller No. 10
NOW Supplements, Methyl Folate 5000 mcg, Superior Bioavailability, 50 Veg Capsules
  • Metabolically Active Folate*
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product...
  • Superior Bioavailability
  • Co-Enzyme B Vitamin
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our...
SaleBestseller No. 11
Doctor's Best Fully Active Folate with Quatrefolic NonGMO Vegan Gluten Free 400 mcg Veggie Caps, 90...
  • Best Fully Active Folate provides MTHF (5-methyltetrahydrofolate), the folate form most directly required for DNA regulation and other fundamental...
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product...
  • Vitamin C is included for added stability.
  • Gluten Free, Non-GMO, Vegan
  • Label images may vary
Bestseller No. 12
Neurobiologix Methylation Complete™ 120 Sublingual Tablets with Bioactive B12, Methyl Folate with...
  • Mood Improvement & Stabilization*
  • Short Term Memory*
  • MTHFR / MTRR Mutations*
  • Sleep Patterns*
  • Immune Health*
Bestseller No. 13
Douglas Laboratories Methyl Folate L-5-MTHF | 1,000 mcg Metafolin Identical to The Naturally...
  • Contains 5-MTHF: Metafolin is directly usable by the body and has been shown to be the only form of folate to cross the blood-brain barrier.*
  • Essential B Vitamin: Folate is a water-soluble essential B vitamin found in many foods, including leafy green vegetables, citrus fruits, and beans...
  • Vitamins/Minerals/Amino Acids: Dietary supplement formulated to provide beneficial support in filling important nutrient gaps.*
  • Our uncompromising operational practices at our state-of-the-art manufacturing facilities surpass GMP standards and manufacturing regulations. All of...
  • For 65 years, Douglas Laboratories has been dedicated to meeting the needs of healthcare professionals. As a globally recognized leader in the...
Bestseller No. 14
L-Methylfolate 15mg - 90 Capsules - Professional Strength Active Methyl Folate - 5-MTHF Supplement...
  • Professional strength: Unlike folic acid, FolateMaxx l-methylfolate 15mg contains biologically active form of 5-methyltetrahydrofolate which is...
  • No nasties, only the good stuff: These vegetarian l methylfolate capsules are made from carefully selected, filler-free, Non-GMO ingredients....
  • Reduce stress: L Methyl folate is the only form of folate that can cross the blood-brain barrier to help facilitate the synthesis of the...
  • Suitable for all diets: We ensure our l methylfolate 15mg supplement is free from most common allergens like gluten, wheat, yeast, shellfish, egg,...
  • Never miss a dose: Our Methylfolates come in 4V capsule size & convenient packaging, making them the smallest available, easy-to-swallow...
Bestseller No. 15
Our Daily Vites L-Methylfolate 15 mg / 15000 mcg Maximum Strength Active Folate, 5-MTHF, Non-GMO,...
  • PURE MAXIMUM STRENGTH - Many supplements contain fillers and other inactive ingredients you just don't need in your supplement. Our Daily Vite's...
  • ASSIST IN REPAIR AND DNA SYNTHESIS OF FOLATE* - Inadequate levels of these ingredients have been linked to diseases, our methylfolate may help...
  • SMALLEST (4V) CAPSULE AVAILABLE. COMPACT ON-THE-GO PACKAGING - Since Our Daily Vites' Methylfolates contain no fillers, our 4V capsule size...
  • 99.9% PURE BIOLOGICALLY ACTIVE METHYLFOLATE- Our powerful formula contains the ingredients necessary for your body to properly utilize folic...
  • THIRD PARTY TESTED FOR PURITY - All of our supplements undergo out of house 3rd party independent testing to guarantee the highest level of...
SaleBestseller No. 16
L Methylfolate 15mg – DNA Verified for Maximum Potency – Superior Bioavailability – 5-MTHF...
  • Fresh Nutrition 5-MTHF L-Methylfolate is DNA Verified and Third Party Tested; Our Bioavailable version also referred to as Folate and Folic Acid is...
  • Vegan Friendly, Non-GMO, Gluten Free, Soy Free, No Artificial Flavors or Colors, No Preservatives, All Natural Ingredients! Our Fully Active B Complex...
  • How Much Do You Get in Each Bottle? Each bottle contains 60 capsules of L Methylfolate providing a dose of 15mg pure DNA Verified 5-MTHF...
  • Our Facility; Fresh Nutrition produces the most potent and highest quality 5-MTHF (L-5-Methyltetrahydrofolate). Our raw ingredients are carefully...
Bestseller No. 17
Methyl-Life Purest L-Methylfolate 10 mg Pharmaceutical Grade Professional Strength Active Folate - 3...
  • THE PUREST ACTIVE FOLATE – Over half of the population may have trouble converting & absorbing folic acid. Methyl-Life carries the purest form of...
  • THERAPEUTIC STRENGTH – Lots of methylfolate products have lower doses (400-1000 mcg). Methyl-Life creates professional dosage levels from 2500-15000...
  • MOOD & COGNITIVE SUPPORT – The only folate form to cross the blood-brain barrier. It helps with neurotransmitter production (i.e. serotonin) which...
  • CLEAN NON-GMO CERTIFIED INGREDIENTS: We make our products dairy and gluten free in a chewable tablet for optimal absorption. No dyes allergens or...
  • CARDIOVASCULAR & NERVE SUPPORT – May help support healthy homocysteine levels which promote heart health and peripheral nerve function. THIS...
Bestseller No. 18
DSO L-Methylfolate(5-MTHF) 10mg 90 Capsules Active Folate Homocysteine Control Anxiety Relief Folic...
  • >ACTIVE FOLATE THAT WORKS - This methylfolate formula contains the ingredients necessary for your body to properly utilize folic acid, also known...
  • THIRD PARTY TESTED - DSO’s supplements all undergo third-party testing to ensure the highest level of purity and quality in the manufacturing...
  • BRAIN & MOOD ASSISTANCE - DSO’s L Methyl Folate is a steller choice for supporting mood, sleep, concentration, hormone support, and energy.
  • DSO IS DOCTOR DESIGNED - As many other leading brands may contain small amounts of L-methylfolate, DSO offers multiple dosages designed specifically...
  • ECO FRIENDLY PACKAGING - we care about the environment, and we think you do too!
Bestseller No. 19
Methyl Folate 15mg (120 Capsules) | Non-GMO, Gluten-Free with Professional Strength Vegan...
  • PREMIUM FAST-ACTING, TOP-QUALITY FOLATE: Considering that 50% of the U.S. population struggles to convert folate into its active form, our...
  • ESSENTIAL VITAMIN B BODY BOOST: L-Methylfolate is an essential B vitamin that is used to treat folate deficiency.
  • NON-GMO, GLUTEN-FREE, AND VEGAN SUPPLEMENT: Our high potency activated L-Methyl Folate is an environmentally friendly and vegan B vitamin supplement...
  • BRAIN, MOOD, AND STABILITY SUPPORT: Methylfolate plays a big role in the production and transportation of neurotransmitters, which regulate...
  • NO FILLERS INCLUDED IN SUPPLEMENT FORMULA: Our methyl folate formula uses zero fillers or excipients like bulking agents, binders, and so forth. We...
Bestseller No. 20
L Methyl Folate 15mg Plus Glycine - 90 Capsules - Active L Methylfolate 5-MTHF Supplement Pills -...
  • Active Form: L-Methylfolate is the active form of folate and is bioavailable. The human body often struggles to convert folic acid into bioavailable...
  • Max Strength: Our Methyl Folate formula contains 15mg of L-Methylfolate and 250mg of L-Glycine per veggie capsule. 90 capsules per bottle for full 90...
  • Amazing Benefits: L-Methylfolate (5-MTHF) supports homocysteine methylation, normal mood, heart health, and supports immune system health....
  • Enhanced With Glycine: We added 250mg of the amino acid L-Glycine to support sleep, heart health, and normal mood. Glycine acts as a neurotransmitter...
  • Many Names and Forms: L-Methylfolate is the bioactive form of folic acid. Methyl Folate is often called L-5-MTHF. It comes in capsules, pills,...

Having trouble finding a great methyfolate?

This problem is well understood by us because we have gone through the entire methyfolate research process ourselves, which is why we have put together a comprehensive list of the best methyfolates available in the market today.

After hours of searching and using all the models on the market, we have found the best methyfolate for 2023. See our ranking below!

How Do You Buy The Best Methyfolate?

Do you get stressed out thinking about shopping for a great methyfolate? Do doubts keep creeping into your mind?

We understand, because we’ve already gone through the whole process of researching methyfolate, which is why we have assembled a comprehensive list of the greatest methyfolate available in the current market. We’ve also come up with a list of questions that you probably have yourself.

John Harvards has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for methyfolate that you consider buying. Your questions might include the following:

  • Is it worth buying an methyfolate?
  • What benefits are there with buying an methyfolate?
  • What factors deserve consideration when shopping for an effective methyfolate?
  • Why is it crucial to invest in any methyfolate, much less the best one?
  • Which methyfolate are good in the current market?
  • Where can you find information like this about methyfolate?

We’re convinced that you likely have far more questions than just these regarding methyfolate, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for methyfolate, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible methyfolate. Make sure that you are only using trustworthy and credible websites and sources.

John Harvards provides an methyfolate buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information.

How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available methyfolate currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of methyfolate has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an methyfolate?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your methyfolate.
  5. Customer Ratings: Number ratings grade methyfolate objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their methyfolate.
  7. Product Quality: You don’t always get what you pay for with an methyfolate, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an methyfolate is should be an indication of how long it will work out for you.

John Harvards always remembers that maintaining methyfolate information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding methyfolate is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly!

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FAQ:

Q: What is another name for methylfolate?

A: It goes by several other common names including: Methylfolate. L-Methylfolate calcium (refers to the calcium salt molecule it is attached to) Metafolin and Deplin. 5-MTHF and L-5-MTHF (in this article 5-MTHF refers to L-5-MTHF) Levomefolic acid. 5-methyltetrahydrofolate. (6S)-5-methyltetrahydrofolate and Quatrefolic.

Q: What is methylfolate (L-MTHF)?

A: It goes by several other common names including: Methylfolate L-Methylfolate calcium (refers to the calcium salt molecule it is attached to) Metafolin and Deplin 5-MTHF and L-5-MTHF (in this article 5-MTHF refers to L-5-MTHF) Levomefolic acid 5-methyltetrahydrofolate (6S)-5-methyltetrahydrofolate and Quatrefolic.

Q: What is L-methylfolate and should you take it?

A: Supplementing L-methylfolate bypasses the body’s natural checkpoints for preventing over-methylation. So we must be incredibly cautious with the dosage, as unnatural levels of folate is linked with several issues including cancer risk (16, 17, 18). As with almost any supplement, this is not something you should take forever.

Q: Is L-methyfolate better than folic acid?

A: Studies show that L-Methyfolate supplementation is equally (if not more) effective than folic acid for increasing circulating folate in those with an MTHFR mutation. It is also highly effective at reducing homocysteine levels in healthy people ( 6, 7 ). It is also better absorbed and interacts with fewer medications than folic acid ( 8 ).