20 Best Antihistamine Cream For Face [2024]

Are you looking for the best antihistamine cream for face? Based on expert reviews, we ranked them. We've listed our top-ranked picks, including the top-selling antihistamine cream for face.

We Recommended:

# Preview Product
1 Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream with Pure Oat Essence, Triple Oat Complex,... Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream with Pure Oat Essence, Triple Oat...
2 PCA SKIN CliniCalm 1% Maximum Strength Hydrocortisone Soothing Cream - Anti Itch Intense Therapy... PCA SKIN CliniCalm 1% Maximum Strength Hydrocortisone Soothing Cream - Anti Itch Intense Therapy...
3 Vanicream 1% Hydrocortisone Anti-Itch Cream - 2 oz - Maximum OTC-Strength Formula for Sensitive Skin Vanicream 1% Hydrocortisone Anti-Itch Cream - 2 oz - Maximum OTC-Strength Formula for Sensitive Skin
4 Clinically Tested Cream for Eczema, Dermatitis and Psoriasis Treatment - Urea 8%, Probiotics w/Best... Clinically Tested Cream for Eczema, Dermatitis and Psoriasis Treatment - Urea 8%, Probiotics...
5 Histafen Antihistamine Itch Calming Cream - Anti Itch Cream Extra Strength Intensive Healing Lotion... Histafen Antihistamine Itch Calming Cream - Anti Itch Cream Extra Strength Intensive Healing...
6 SkinSmart Antimicrobial Eczema Therapy with Hypochlorous Acid, Removes Bacteria so Skin Can Heal,... SkinSmart Antimicrobial Eczema Therapy with Hypochlorous Acid, Removes Bacteria so Skin Can Heal,...
7 LEMYKA Eczema Lotion for dry itchy skin- Rosacea treatment Face Rash Cream- Itch Redness Relief for... LEMYKA Eczema Lotion for dry itchy skin- Rosacea treatment Face Rash Cream- Itch Redness Relief...
8 Benadryl Extra Strength Anti-Itch Gel, 2 Percentage Diphenhydramine HCI Topical Analgesic &... Benadryl Extra Strength Anti-Itch Gel, 2 Percentage Diphenhydramine HCI Topical Analgesic &...
9 Cortizone 10 Intensive Healing Lotion for Eczema 3.5 oz., Maximum Strength 1% Hydrocortisone With... Cortizone 10 Intensive Healing Lotion for Eczema 3.5 oz., Maximum Strength 1% Hydrocortisone With...
10 Benadryl Anti-Itch Cream Benadryl Anti-Itch Cream
11 Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling... Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling...
12 Boericke & Tafel Florasone Cardiospermum Cream (Nature's Way Brands) Boericke & Tafel Florasone Cardiospermum Cream (Nature's Way Brands)
13 Remedy Tea Tree Oil Balm - Cream for Athletes Foot, Jock Itch, Ringworm, Eczema, Nail Issues, Rash,... Remedy Tea Tree Oil Balm - Cream for Athletes Foot, Jock Itch, Ringworm, Eczema, Nail Issues,...
14 National Eczema Association Accepted Cream, Colloidal Oatmeal Lotion for Dry, Itchy Skin Relief,... National Eczema Association Accepted Cream, Colloidal Oatmeal Lotion for Dry, Itchy Skin Relief,...
15 Manuka Relief Cream for Eczema Psoriasis Shingles Prone, Dry Skin- Colloidal Oatmeal & Manuka Honey-... Manuka Relief Cream for Eczema Psoriasis Shingles Prone, Dry Skin- Colloidal Oatmeal & Manuka...
16 Healthy Skin Kitchen: For Eczema, Dermatitis, Psoriasis, Acne, Allergies, Hives, Rosacea, Red Skin... Healthy Skin Kitchen: For Eczema, Dermatitis, Psoriasis, Acne, Allergies, Hives, Rosacea, Red...
17 Histafen Antihistamine Extra Strength Itch Relief Spray - Anti Itch Spray For People Skin Healing... Histafen Antihistamine Extra Strength Itch Relief Spray - Anti Itch Spray For People Skin Healing...
18 Cortizone 10 Maximum Strength Plus Ultra Moisturizing 2 oz., 1% Hydrocortisone Anti-Itch Creme Cortizone 10 Maximum Strength Plus Ultra Moisturizing 2 oz., 1% Hydrocortisone Anti-Itch Creme
19 CeraVe Moisturizing Lotion for Itch Relief | Anti Itch Lotion with Pramoxine Hydrochloride |... CeraVe Moisturizing Lotion for Itch Relief | Anti Itch Lotion with Pramoxine Hydrochloride |...
20 Cortizone 10 Maximum Strength Ointment 2 oz., 1% Hydrocortisone Ointment for Itch Relief Cortizone 10 Maximum Strength Ointment 2 oz., 1% Hydrocortisone Ointment for Itch Relief
SaleBestseller No. 1
Aveeno Maximum Strength 1% Hydrocortisone Anti-Itch Cream with Pure Oat Essence, Triple Oat Complex,...
  • Aveeno Maximum-Strength 1% Hydrocortisone Anti-Itch Cream provides effective and long-lasting relief of itchy skin
  • This maximum-strength itch relief cream is designed to soothe irritated skin due to minor irritations, inflammation and rashes
  • Enriched with skin-soothing aloe, nourishing vitamin E and Triple Oat Complex with pure oat essence, this unique formula helps relieve dry, itchy skin
  • Use on skin affected by eczema, seborrheic dermatitis, psoriasis, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics or...
  • From the dermatologist-recommended skincare brand for over 65 years, Aveeno uses the goodness of nature and the power of science to keep skin healthy...
Bestseller No. 2
PCA SKIN CliniCalm 1% Maximum Strength Hydrocortisone Soothing Cream - Anti Itch Intense Therapy...
  • Calming ingredient blend soothes the skin after non-invasive professional treatments, waxing and shaving
  • Ideal for itch and irritation relief due to eczema, psoriasis, dermatitis or other topical allergens
  • Soothes the skin, relieving redness, inflammation and irritation
Bestseller No. 3
Vanicream 1% Hydrocortisone Anti-Itch Cream - 2 oz - Maximum OTC-Strength Formula for Sensitive Skin
  • Ultimate relief: Our anti-itch cream with maximum over-the-counter strength provides fast relief from flare-ups due to eczema, dermatitis and...
  • Mild formula: This gluten-free hydrocortisone cream does not cause blackheads and can be used on the face
  • Free of common chemical irritants: Our products are free of dyes, fragrance, masking fragrance, lanolin, parabens and formaldehyde releasers
  • Dermatologist tested: Vanicream products are formulated with ingredients dermatologists consider desirable and not irritating or sensitizing to the...
  • Directions: Apply as needed or as directed by a doctor
SaleBestseller No. 4
Clinically Tested Cream for Eczema, Dermatitis and Psoriasis Treatment - Urea 8%, Probiotics w/Best...
  • MAKE PEACE WITH YOUR BODY by relieving the 4 symptoms of extra dry skin - redness, roughness, itching and flaking. Our breakthrough formula seals in...
  • Glow on The Go: 5 INDIVIDUAL SACHETS INCLUDED. Long weekend, family vacation with kids, European backpacking trip, and everything in between. Wherever...
  • IT’S ALL BEHIND THE SCENES: The synergy of the powerful moisturizing complex (8% urea, hyaluronic acid and shea), working together with yogurt...
  • SAFETY FIRST: The Best Choice for Your Family. Hypoallergenic, Paraben-, Preservative- & Steroid-free, it contains no artificial fragrances, thus...
  • FEEL AS GOOD AS YOU LOOK: Let your inner zen show with skin that is soft, smooth and healthy. Peaceful Skin, Peaceful Mind ~ In the unlikely case that...
Bestseller No. 5
Histafen Antihistamine Itch Calming Cream - Anti Itch Cream Extra Strength Intensive Healing Lotion...
  • ✔️ Suffer from Histamine Intolerance or Mast Cell Activation Syndrome (histamine release that causes itching all over body or in specific areas...
  • ✔️ Creams on the market do not address the issue of histamine issues. The only thing recommended is an antihistamine cream but medications can...
  • ✔️ Our Histafen moisturizing cream cools and softens the skin WITHOUT ingredients that promote additional histamine to be released from mast...
  • ✔️ This moisturizing cream does not cause histamine block but calms the skin itch (as an overnight itch relief creme) and does not have histamine...
  • ✔️ Combines blue tansy essential oils along with roman chamomile essential oil, peppermint essential oil, clove oil essential oil, fennel oil,...
SaleBestseller No. 6
SkinSmart Antimicrobial Eczema Therapy with Hypochlorous Acid, Removes Bacteria so Skin Can Heal,...
  • NEW APPROACH for problem skin. SkinSmart targets bacteria linked to 70% of eczema conditions
  • HELPS HEAL with the antimicrobial benefits of Hypochlorous. If lotions have failed, it's time to try SkinSmart
  • FAST RELIEF; Prescription-strength spray helps heal eczema, rosacea and more. STOPS ITCH from rashes and contact dermatitis.
  • NATURAL INGREDIENTS are safe for scalp, eyelids and sensitive skin
  • RATED 5/5 STARS BY THE NATIONAL ECZEMA ASSOCIATION; Steroid-free and cleared for all ages, Actual Product Style and Design may vary
Bestseller No. 7
LEMYKA Eczema Lotion for dry itchy skin- Rosacea treatment Face Rash Cream- Itch Redness Relief for...
  • IDEAL FACE RASH CREAM – Perfect treatment lotion for eczema, rosacea, hives, contact or seborrheic dermatitis, heat rash for kids as well as adults....
  • SAFE AND GENTLE – LEMYKA healing lotion is formulated with natural and pure ingredients free of any steroids, parabens, irritants, toxins, and GMOs....
  • ADVANCED FORMULA – Our team of skincare experts have formulated this rash relief cream to achieve noticeable improvement. Its unique non-greasy...
  • POWERFUL PLANT ACTIVES - Packed with ALOE VERA, VITAMIN E, HYALURONATE, PANTHENOL, and nourishing PLANT OILS, this soothing moisturizer calms down...
  • OUR COMMITMENT – We guarantee your complete satifsfaction or your money back! Our products are quality assured, made freshly here in the USA. Skin...
Bestseller No. 8
Benadryl Extra Strength Anti-Itch Gel, 2 Percentage Diphenhydramine HCI Topical Analgesic &...
  • 3.5-ounce tube of Benadryl Extra-Strength Anti-Itch Gel temporarily relieves pain and itching associated with insect bites, minor burns, sunburn,...
  • Topical analgesic gel , works when you need it most and provides cooling, anti-itch relief from most minor pains and outdoor itches associated with...
  • The cooling gel provides the relief of pain and itching associated with sunburn, relieves outdoor itches associated with poison ivy, insect bites and...
  • Cooling gel that provides relief from most outdoor itches contains 2% of the topical analgesic pain reliever diphenhydramine hydrochloride that works...
  • Intended for use by those ages 2 and up, soothing gel offers itch relief for kids and adults alike and is great to keep on hand for relief during...
SaleBestseller No. 9
Cortizone 10 Intensive Healing Lotion for Eczema 3.5 oz., Maximum Strength 1% Hydrocortisone With...
  • Contains one (1) 3.5-oz. tube of Cortizone 10 Maximum Strength Intensive Healing Lotion for Eczema
  • FAST, LASTING RELIEF: This lotion is for relief of itching associated with rashes, minor skin irritation and inflammation due to eczema
  • STOP THE ITCHSANITY: Cortizone 10 Eczema Lotion contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors
  • 7 INTENSIVE MOISTURIZERS: Cortizone 10 Anti-Itch Lotion for Eczema features 7 moisturizers plus vitamins A, C & E to hydrate eczema-affected skin
  • Adults and children 2 years of age and older: Apply to the affected area not more than 3 to 4 times daily
Bestseller No. 10
Benadryl Anti-Itch Cream
  • 1-ounce tube of Benadryl Original-Strength Anti-Itch Stopping Cream to provide relief from most outdoor itches
  • Topical cream temporarily relieves itching associated with insect bites, sunburn, scrapes, minor skin irritations, burns, and cuts.
  • Formula contains with 1% diphenhydramine hydrochloride topical analgesic and 0.1% zinc acetate skin protectant
  • Cream contains a histamine blocker and dries the oozing and weeping of poison ivy, poison oak, and poison sumac. Is intended for use by those ages 2...
  • Topical Analgesic.
SaleBestseller No. 11
Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling...
  • ARNICA FOR PAIN: This homeopathic medicine helps temporarily relieve muscle pain & stiffness due to minor injuries, overexertion & falls. Also great...
  • TOPICAL PAIN RELIEF: Our non-greasy, water-based formula absorbs quickly & is unscented & paraben-free. This cooling gel is great for relief following...
  • PLANT-BASED ACTIVE INGREDIENT: The Arnica montana plant is a natural pain reliever. This popular homeopathic medicine temporarily relieves muscle pain...
  • HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments...
  • THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a...
SaleBestseller No. 12
Boericke & Tafel Florasone Cardiospermum Cream (Nature's Way Brands)
  • Homeopathic free of cortisone.
  • Relief for itches and rashes and can be used to help soothe dry skin, itching and inflammation from eczema, rashes, and skin allergies.**
  • Contains a tincture of Cardiospermum halicacabum, a flowering tropical vine that has been used in India and Africa for centuries.
  • Non-greasy, fast-absorbing cream with a pleasant fragrance.
  • These indications are based solely on traditional homeopathic use. They have not been evaluated by the Food & Drug Administration.
SaleBestseller No. 13
Remedy Tea Tree Oil Balm - Cream for Athletes Foot, Jock Itch, Ringworm, Eczema, Nail Issues, Rash,...
  • Fight skin infections and eczema with Remedy Balm - Premium organic grade tea tree, eucalyptus and lavender essential oils form a powerful foot and...
  • Soothing relief from itchy, cracked, inflamed, sore, and irritated skin - Our tea tree cream helps relieve jock itch, itchy feet, scaling, itching...
  • 100% organic and natural tea tree, eucalyptus, and lavender oil - Our premium therapeutic tea tree cream contains skin moisturizing Omega 3,6,7,9, and...
  • Ideal for all skin types - TruRemedy Naturals premium body balm for women and men works great for multiple skin types and conditions. Our Remedy balm...
  • TruRemedy Naturals 100% Guarantee – Remedy Balm, Remedy Soap Bars, Remedy Soap Body Wash, Remedy Hemorrhoid Balm, Remedy Bruise Cream, Natural...
Bestseller No. 14
National Eczema Association Accepted Cream, Colloidal Oatmeal Lotion for Dry, Itchy Skin Relief,...
  • Hydrates and Softens Dry, Rough Skin: Packed with nutrient dense natural botanicals and intensely moisturizing oils, this formula is designed to...
  • Fast Acting Itch Relief: Our plant-based cream is ultra hydrating and soothing to dry itchy skin. It's accepted by National Eczema Association and...
  • Helps Control Flare-Ups: Powered by amaranth seed oil and shea butter to nourish the skin's barrier, hyaluronic acid to lock in moisture, and MSM to...
  • Healthy Skin that Lasts: Formulated with science-backed ingredients that are clinically studied to support the continued maintenance of healthy skin
  • Accelerate Your Results: Purchase this gentle yet highly effective moisturizer to intensely nourish and hydrate dry, itchy, cracked skin. Or get our...
SaleBestseller No. 15
Manuka Relief Cream for Eczema Psoriasis Shingles Prone, Dry Skin- Colloidal Oatmeal & Manuka Honey-...
  • 🍯MANUKA HONEY RELIEF 🐝- Made with pure New Zealand Manuka Honey, which has soothing, nourishing properties for unhappy, eczema prone skin.
  • 🌿ALL NATURAL, PLANT-BASED- Manuka Relief has a natural formula containing plant-based and nutrient rich ingredients.
  • 🏥ADVANCED FORMULA- Manuka Honey, Colloidal Oatmeal, Arnica Montana Flower Extract along with other natural proven ingredients, helps provide...
  • 🧡STOP ITCHING AND START RESTORING- Manuka Relief can be used as a daily, nourishing moisturizer for all ages!
  • 🇺🇸MADE IN USA, LIFETIME MONEYBACK GUARANTEE- Clearbody Organics is a proud USA company where quality comes first AND we offer a Lifetime Money...
SaleBestseller No. 16
Healthy Skin Kitchen: For Eczema, Dermatitis, Psoriasis, Acne, Allergies, Hives, Rosacea, Red Skin...
  • Hardcover Book
  • Fischer, Karen (Author)
  • English (Publication Language)
  • 224 Pages - 03/09/2021 (Publication Date) - Exisle Publishing (Publisher)
Bestseller No. 17
Histafen Antihistamine Extra Strength Itch Relief Spray - Anti Itch Spray For People Skin Healing...
  • ✔️ STOP SUFFERING from Histamine Intolerance or Mast Cell Activation Syndrome!
  • ✔️ GET ITCH RELIEF from Histamine release causing itching all over body or in specific areas (shoulders, elbows, wrists, knees, back)
  • ✔️ CALM THE ITCH with Histafen spray! Spray itchy skin area and calm the itch!
  • ✔️ UNIQUELY BALANCED FORMULATION of natural essential oils that soothe and heal
  • ✔️ COOL, CLEANSE and soften the skin WITHOUT ingredients that promote additional histamine to be released from mast cells
Bestseller No. 18
Cortizone 10 Maximum Strength Plus Ultra Moisturizing 2 oz., 1% Hydrocortisone Anti-Itch Creme
  • CONTAINS: One (1) 2-oz. tube of Cortizone 10 Maximum Strength Plus Ultra Moisturizing Anti-Itch Crème
  • FAST & LONG LASTING: Cortizone 10 Ultra Moisturizing Anti-Itch Creme relieves itching fast and lasts for hours
  • STOP THE ITCHSANITY: This maximum strength anti-itch creme contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors
  • 10 NOURISHING INGREDIENTS: Cortizone 10 Plus Ultra Moisturizing contains 10 moisturizers, including aloe, and vitamins A and E to help make skin feel...
  • RELIEVES ITCH: Maximum Strength Cortizone 10 helps relieve itch associated with minor skin irritations and rashes due to insect bites, psoriasis,...
Bestseller No. 19
CeraVe Moisturizing Lotion for Itch Relief | Anti Itch Lotion with Pramoxine Hydrochloride |...
  • [ CERAVE ANTI ITCH LOTION ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Lightweight...
  • [ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe...
  • [ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm...
  • [ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are...
  • [ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face, body, and hands to temporarily relieve itching. Holds National Eczema Association (NEA)...
Bestseller No. 20
Cortizone 10 Maximum Strength Ointment 2 oz., 1% Hydrocortisone Ointment for Itch Relief
  • CONTAINS: One (1) 2-oz. tube of Cortizone 10 Maximum Strength Ointment
  • FAST RELIEF: Cortizone 10 Anti-Itch Ointment relieves itching fast and lasts for hours
  • STOP THE ITCHSANITY: Cortizone 10 Ointment contains maximum strength hydrocortisone, the #1 itch medicine recommended by doctors
  • RELIEVES ITCH: Maximum Strength Cortizone 10 helps relieve itch associated with minor skin irritations and rashes due to insect bites, psoriasis,...
  • WATER-RESISTANT FORMULA: This anti-itch ointment locks in moisture and helps keep the affected area clean while hydrocortisone relieves the itch

Having trouble finding a great antihistamine cream for face?

This problem is well understood by us because we have gone through the entire antihistamine cream for face research process ourselves, which is why we have put together a comprehensive list of the best antihistamine cream for faces available in the market today.

After hours of searching and using all the models on the market, we have found the best antihistamine cream for face for 2023. See our ranking below!

How Do You Buy The Best Antihistamine Cream For Face?

Do you get stressed out thinking about shopping for a great antihistamine cream for face? Do doubts keep creeping into your mind?

We understand, because we’ve already gone through the whole process of researching antihistamine cream for face, which is why we have assembled a comprehensive list of the greatest antihistamine cream for face available in the current market. We’ve also come up with a list of questions that you probably have yourself.

John Harvards has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for antihistamine cream for face that you consider buying. Your questions might include the following:

  • Is it worth buying an antihistamine cream for face?
  • What benefits are there with buying an antihistamine cream for face?
  • What factors deserve consideration when shopping for an effective antihistamine cream for face?
  • Why is it crucial to invest in any antihistamine cream for face, much less the best one?
  • Which antihistamine cream for face are good in the current market?
  • Where can you find information like this about antihistamine cream for face?

We’re convinced that you likely have far more questions than just these regarding antihistamine cream for face, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for antihistamine cream for face, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible antihistamine cream for face. Make sure that you are only using trustworthy and credible websites and sources.

John Harvards provides an antihistamine cream for face buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information.

How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available antihistamine cream for face currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of antihistamine cream for face has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an antihistamine cream for face?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your antihistamine cream for face.
  5. Customer Ratings: Number ratings grade antihistamine cream for face objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their antihistamine cream for face.
  7. Product Quality: You don’t always get what you pay for with an antihistamine cream for face, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an antihistamine cream for face is should be an indication of how long it will work out for you.

John Harvards always remembers that maintaining antihistamine cream for face information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding antihistamine cream for face is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly!

Related Post:

FAQ:

Q: Which face cream is best?

A: CeraVe AM and CeraVe PM face creams are ideal for those with sensitive skin. If you have oily skin, you still need to moisturize, and experts and users agree that Olay Regenerist Micro-Sculpting Cream is a top choice.

Q: What is the best anti aging cream for face?

A: Active Retinol Complex. With daily, long-term use, the Baebody Retinol Moisturizer Cream can also improve the texture around your face, eyes, and neck while diminishing the appearance of age spots and other discolorations. It has a super anti-aging formula, which is great for hydrating dry skin while reducing the visible signs of aging.

Q: Can you use clotrimazole and betamethasone cream on your face?

A: Do not use betamethasone and clotrimazole cream on the face or underarms. This medicine may raise the chance of cataracts or glaucoma. Talk with the doctor. If you are 65 or older, use betamethasone and clotrimazole cream with care.

Q: What is a natural antihistamine for topical use on skin?

A: The 4 Best Natural Antihistamines Stinging nettle. A common herb in natural medicine, stinging nettle, may also be a natural antihistamine. … Quercetin. Quercetin is an antioxidant found naturally in onions, apples, and other produce. … Bromelain. Bromelain is a compound most commonly found in pineapples, but you can also find it in supplement form. Butterbur. …